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Because steroids can cause you to put on weight or have an increased appetite, it’s important to keep an eye on your weight while taking them. Making sensible food choices and including some physical activity in your daily routine should help you avoid putting on weight. Steroids can weaken bones, which can lead to a condition known as osteoporosis. This condition makes it more likely that you’ll fracture your bones, sometimes after very minor falls or bumps. Your doctor may advise you to take drugs called bisphosphonates, or calcium and vitamin D supplements, along with the steroids to help prevent this. Regular exercise, especially things that involve your bones carrying the weight of your body, such as walking, can also help to reduce the risk of getting osteoporosis. You should also make sure you get enough calcium in your diet, and avoid smoking and drinking too much alcohol. Effects on other treatments. Steroids can be taken along with other drugs. 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