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In women, these hormones stimulate egg production and ovulation, whereas in men, they increase testosterone production and sperm synthesis. Both FSH and LH are natural hormones that are required for healthy sperm production: FSH is needed to support sperm maturation during spermatogenesis, while LH stimulates the synthesis and secretion of testosterone. Testosterone is the principal male sex hormone and is needed for making sperm. Low testosterone production cannot support healthy sperm synthesis and thus, causes infertility. Because Clomid indirectly boosts testosterone levels in men, it can be used to treat infertility that results from low testosterone production. Clomid for Male Infertility Clomid is typically taken once a day, with a staring dose of 25 mg per day. However, the dosage often needs to be adjusted later on, as the individual response to the medication varies. 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