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Injecting steroids into the epidural space can decrease inflammation and decrease or. Steroid injections are used most commonly for knee and shoulder. A lumbar epidural steroid injection may be used to reduce the inflammation around the spinal nerves. During the procedure, the patient lies down with a cushion. An epidural steroid injection treats back, neck, leg, and arm pain caused by: sciatica; spinal stenosis; a herniated disc; osteoarthritis; bone spurs. — sciatica treatment may include a steroid medication to reduce inflammation that causes low back and leg pain. An oral (by mouth) steroid. Vastus lateralis muscle of the thigh. The thigh may be used when the other sites aren’t available or if you need to administer the medication on your own. Epidural steroid injections can help relieve pain in your back or legs caused by sciatica. 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