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Introduction Clenbuterol is an orally active, potent, and selective beta-2 adrenoceptor agonist (causes bronchodilation), used in the treatment of asthma in European countries Kamburoff et al (1977) Tschan et al (1979) Daubert et al (2007) Kamalakkannan et al (2008). Human pregnancy and that it accumulates in the pla- centa. Key words: clenbuterol, pregnancy, placental trans- fer; fetal concentration, placental concentration, am- niotic fluid concentration, maternal plasma level, ma- ternal-fetal concentration ratio Clenbuterol I is an fl2-adrenergic receptor agonist,. Pregnancy and Breastfeeding: Clenbuterol has not been extensively studied in pregnant or breastfeeding women, and its effects on fetal development or lactation are unknown. It is recommended to avoid Clenbuterol during pregnancy and while breastfeeding to prioritize the health and safety of both the mother and the baby. 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