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The immunosuppressant drugs suppress your body’s ability to do this. — testosterone therapy can cause changes in your menstrual cycle. From people asking us how taking testosterone will affect their cycle. — it has predominantly glucocorticoid activity and low mineralocorticoid activity, which means it affects the immune response and inflammation. Steroids can affect the way the body controls blood sugar levels and this. — menstrual irregularities in women. Steroid abuse can also lead to significant psychiatric and behavioral issues. One of the most common issues. Anabolic steroid use can be addictive and, therefore, difficult to stop. Because oral and injectable testosterone is inactive, testosterone esters and. Menstrual irregularities (missed or no periods); oily skin; tissue damage at injection site. 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