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Mice with muscular dystrophy that received weekly prednisone were stronger and performed better on the treadmill than those that received a placebo. When prednisone was given every day, the muscles atrophied and wasted. McNally, also a professor of Medicine in the Division of Cardiology and of Biochemistry and Molecular Genetics, initiated the research because she wanted to understand how prednisone ‘ which is given to treat individuals with a form of muscular dystrophy called Duchenne Muscular Dystrophy ‘ prolongs patients’ ability to walk independently and stay out of a wheelchair. Only boys get Duchenne Muscular Dystrophy because it is on the X chromosome, and males have only one X chromosome. This technique uses a laser to poke a hole in muscle cells. Then the muscle cell is observed in real time as it reseals the hole, a natural repair process. Next, the scientists tested to see if steroids could boost the repair process. 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