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We have been interested in seeing whether nandrolone alters the direct nerve chemical and behavioural effects of cocaine in laboratory animals. We have also sought to find out whether there are sustainable changes to nerve pathways in the brain caused by administering nandrolone, and after how long the changes will disappear. Our results definitely show that nandrolone has long-lasting effects on the brain dopaminergic and serotonergic nervous system. Although nandrolone levels apparently decreased and eventually disappeared completely in rat blood, nandrolone-induced changes were still detectable. Serotonin system recovery lasted, in turn, six times the duration of the administration period, buy letroz 2.5 mg antiestrogens femara. Anabolic steroid induced changes in the central nervous system’s dopamine and serotonin systems therefore seem to recover, but it takes a considerably long time compared to the duration of the administration period. 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