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This could result in a permanent inadequate gonadal function. Cycles on the HCG should be kept down to around 3 weeks at a time with an off cycle of at least a month in between. For example, one might use the HCG for 2 or 3 weeks in the middle of a cycle, and for 2 or 3 weeks at the end of a cycle, buy hgh 191aa – grey tops 120iu human growth hormone $330.00 human growth hormone, hgh. It has been speculated that the prolonged use of HCG could permanently, repress the body own production of gonadotropins. This is why short cycles are the best way to go. HCG Pregnyl 1500iu SIDE EFFECTS: As noted earlier, the primary risk associated with human chorionic gonadotropin is causing testicular desensitization and damage to the Leydig cells of the testes resulting in permanent impairment to natural testosterone production. It is the aromatase activity that occurs with HCG that some feel is actually toxic to the Leydig cells of the testes. If this sceanrio plays out an individual would be causing permanent damage to their natural testosterone production (hypogonadism). This is why relatively small doses of the compound should be administered at a time. If large doses are taken it is likely that some damage may occur. One way to minimize the risk of permanent damage is to use tamoxifen throughout the administration of HCG. Studies have shown that human chorionic gonadotropin can, at least partially, block the conversion of 17 alpha-hydroxyprogesterone (17 OHP), which is a testosterone precursor, to testosterone. Obviously this is something that a user would want to avoid. However tamoxifen has been shown to protect against this effect quite effectively. Therefore, it would appear that by using tamoxifen while running HCG a user could help to ensure that desensitization of the testes does not occur. However, it should be noted that if a user is not running large amounts of human chorionic gonadotropin desensitization should not be an issue and tamoxifen would be unnecessary. Despite this, for those users that administer large amounts of HCG it is advisable that they also use tamoxifen for this reason. Due to the fact that there exists luteinizing hormone and human chorionic gonadotropin receptors in various tissues in the body other then gonadal, this indicates that human chorionic gonadotropin can have an effect on these tissues resulting in possible negative side effects when administered. Such case of this is the possible development of gynecomastia in users. It appears that the use of human chorionic gonadotropin in a small number of users has resulted in some men developing gynecomastia that is not related to their estrogen levels or increased levels of prolactin, the most obvious causes of gynecomastia in steroid users. Rather, in a very small minority of users it seems that the increased amount of circulating luteinizing hormone or the human chorionic gonadotropin itself can interact with these receptors in the breast tissue causing a reaction resulting in the development of gynecomastia. It is unknown at this time the actual mechanism by which this is accomplished, but it does appear to occur frequently in a small number of men. As well there is no known method to combat this side effect in men who experience it, leaving the only option to treat this effect the cessation of human chorionic gonadotropin administration altogether. Fortunately it appears that when this is done the gynecomastia that has developed begins to dissipate rapidly and becomes unnoticeable within a matter of days or weeks in the majority of cases. So knowing that the ability of the testes to aromatize androgens could potentially be heightened several times greater than normal when using HCG, it is fairly obvious that it should only be used as a quick stimulus to the testes and not something that is used to constantly barrage them in an attempt to keep them functioning.
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